Utilizing superior knowledge science instruments to assist environmental well being analysis in Africa was the main target of a Sept. 23 seminar, a part of a collection on the state of data science. The collection is sponsored by Harnessing Knowledge Science for Well being Discovery and Innovation in Africa (DS-I Africa), a program of the Nationwide Institutes of Well being (NIH) Frequent Fund (see sidebar).

man drawing a chart using a touch screen interfaceKnowledge science approaches assist characterize hazardous exposures in Africa, join exposures to well being outcomes, and scale back danger of illness related to the atmosphere.

NIEHS Performing Deputy Director Gwen Collman, Ph.D., moderated the panel. Chris Duncan, Ph.D., from the institute’s Genes, Environment, and Health Branch, co-organized the seminar.

Integrating numerous knowledge sources

Gwen Collman, Ph.D.Collman beforehand directed the NIEHS Division of Extramural Analysis and Coaching and was an energetic member of the Human Heredity and Health in Africa consortium. (Picture courtesy of Steve McCaw)

Collman emphasised the complicated problem of documenting an individual’s exposures. Researchers draw on sources reminiscent of these listed under, mixed with geospatial (geographic info system, or GIS) or temporal satellite tv for pc knowledge, she defined.

  • Sampling air, water, and soil both instantly or with sensors.
  • Private biomonitoring.
  • Molecular-level markers of publicity in biosamples.

“One of many main challenges of our discipline is integrating all these streams of knowledge [so] that we will usefully depict publicity over an individual’s lifetime, a discipline referred to as exposomics,” Collman mentioned.

Three panelists shared their experiences.

Overcoming human limitations

Exposome knowledge are collected in Africa however gaps stay within the content material and entry to it. Computational strategies and instruments are wanted to make complicated knowledge helpful to well being professionals and policymakers.

Berhane mentioned machine studying, significantly predictive fashions. As a result of extra knowledge are usually not essentially higher knowledge, researchers can use human-supervised machine studying to weed out messy or incomplete info. For instance, hospital knowledge, obtainable in digital kind in a lot of the developed world, is manually collected in African hospitals.

“Africa is already going through a number of challenges, reminiscent of a variety of exposures mixed with fast urbanization and industrialization,” mentioned Berhane. “Within the face of all this, there’s a scarcity of high-quality knowledge and restricted human capability in these areas.”

Group-focused instruments

Finish-to-end knowledge methods are being developed to handle urgent environmental well being issues like air air pollution. From knowledge assortment {hardware} to making use of machine studying and knowledge science strategies, such methods can generate spatial and temporal air high quality patterns throughout a metropolis.

In Uganda’s capital Kampala, Bainomugisha applies computational strategies and instruments to the town’s environmental well being challenges. He’s the challenge lead for AirQo (see sidebar), which builds and deploys customized internet-connected gadgets to measure air high quality, for instance, mounting them on roofs or motor scooters. Policymakers can use the info to develop rules to guard well being, he defined.

“When consultants in fields like laptop science work on environmental well being points, we will get new improvements,” Collman noticed. “For instance, the boda boda scooters are one of many predominant sources of transportation round Kampala. The novelty right here is that they take readings each 90 seconds and create very massive, geo-tagged, real-time datasets that may map air air pollution ranges across the metropolis.”

air monitoring equipment, Makerere School of Public HealthAir monitoring gear atop the Makerere College of Public Well being. (Picture courtesy of Gwen Collman)

Taking knowledge again to the folks

In South Africa, Wright merges GIS, meteorological, socioeconomic, qualitative, scientific, and different knowledge to gather proof for motion and decision-making. Her research of human well being results of the rise in hotter days supported improvement of a warmth well being early warning system based mostly on predictive modeling.

Nevertheless, high-level policymakers are usually not the one viewers of curiosity, Wright emphasised. The folks most affected by exposures also needs to have entry, for making native selections. “We actually want to consider methods to make knowledge significant,” she mentioned, suggesting science communicators may help shut the hole.

New analysis funding

“This program goals to construct [research] capability and advance knowledge science analysis to catalyze innovation in well being analysis and well being care on the African continent,” mentioned Duncan.

“There are a number of new funding opportunities on the road,” he famous. “This symposium is related to the launch of the brand new program.” The primary due dates for making use of are in late November.

(Kelley Christensen is a contract author and editor for the NIEHS Workplace of Communications and Public Liaison.)




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